Sequence information is generated for three chromosomes with a length of 150 Megabases (Mb). The genome simulated has a high degree of short-range LD (Ne70). The SNP panel contains 12,000 markers (i.e. 4,000 markers per chromosome). For each chromosome, 150 randomly placed QTL and zero FTL mutations were generated. The quantitative trait simulated has a narrow sense heritability of 0.35 and only additive effects are generated (i.e. no dominance). The phenotypic variance is by default set at 1.0, and therefore the residual variance is 0.65. The founder population consisted of 25 males and 200 females. Random selecton of progeny and culling of parents was conducted for 3 generations. For each generation, a total of 25 males and 200 females are in the population. A total of 5 and 40 (0.2 replacement rate) male and female parents, respectively, are culled and replaced by new progeny each generation. After 3 generations, animals with a high EBV were selected or culled each generation. A total of 10 generations were simulated. The EBV are estimated using an animal model with a pedigree-based relationship matrix. Each mating pair produced eight progeny. Within each full-sib family a maximum of 2 progeny can be selected. Parents that had pedigree-based relationships greater than 0.125 were avoided, and this was optimized based on the simulated annealing method.