QTL/FTL Distribution Parameters
ADD_QUAN
- Description: The parameters for the gamma distribution that generate the un-scaled additive effect for QTL. The effects are scaled to the user specified additive genetic variance. A complete description is outlined HERE.
- Options:
- Shape: Shape of gamma distribution.
- Scale: Scale of gamma distribution.
- Usage: 'ADD_QUAN: 0.4 1.66'.
- Type: Optional. Default is 0.4 1.66.
DOM_QUAN
- Description: The parameters for the normal distribution that generate the degree of dominance (h) for QTL. The effects are scaled to the user specified dominance genetic variance. A complete description is outlined HERE.
- Options:
- Mean: Mean of a normal distribution.
- Standard Deviation (SD): SD of a normal distribution.
- Usage: 'DOM_QUAN: 0.1 0.2'.
- Type: Optional. Default is 0.1 0.2.
LTHA
- Description: The parameters for the gamma distribution that generate the selection coefficients for lethal FTL. A complete description is outlined HERE.
- Options:
- Shape: Shape of gamma distribution.
- Scale: Scale of gamma distribution.
- Usage: 'LTHA: 900.0 0.001'.
- Type: Optional. Default is 900.0 0.001.
LTHD
- Description: - The parameters for the normal distribution that generate the degree of dominance for the lethal FTL. A complete description is outlined HERE.
- Options:
- Mean: Mean of a normal distribution.
- Standard Deviation (SD): SD of a normal distribution.
- Usage: 'LTHD: 0.001 0.0001'.
- Type: Optional. Default is 0.001 0.0001.
SUBA
- Description: - The parameters for the gamma distribution that generate the selection coefficients for sublethal FTL. A complete description is outlined HERE.
- Options:
- Shape: Shape of gamma distribution.
- Scale: Scale of gamma distribution.
- Usage: 'LTHD: 0.1 0.2'.
- Type: Optional. Default is 0.1 0.2.
SUBD
- Description: - The parameters for the normal distribution that generate the degree of dominance for sublethal FTL. A complete description is outlined HERE.
- Options:
- Mean: Mean of a normal distribution.
- Standard Deviation (SD): SD of a normal distribution.
- Usage: 'LTHD: 0.3 0.1'.
- Type: Optional. Default is 0.3 0.1.
COVAR
- Description: - Determines the relationship between the additive effect of the quantitative trait and selection coefficient for the sub-lethal trait. The relationship is a function of the number of QTL that impact the quantitative and sub-lethal trait and the rank correlation between the effects. A complete description is outlined HERE.
- Options:
- double (0.0-1.00): Proportion of QTL that have both a quantitative and sub-lethal effect.
- double (0.0-1.00): Genetic correlation: Rank correlation between QTL and FTL effects.
- Usage: 'COVAR: 0.5 0.2'.
- Type: Optional. Default is 0.0 0.0.
- Note:
Fitness values range from 0 to 1 and higher values leading to a lower fitness value. If the two traits are antagonistic under the scenario of high values being favorable, the correlation should be positive. One just needs to change the favorable direction of the quantitative trait to alter the interpretation.